at the moment Audio out is rendered like System Sound output. That means all System Sounds played back beside Clarity Audio.
I think a helpful Feature is, to specify separate audio interface (in my case Motu) to Playback Audio From Clarity. The system out is furthermore on System Audio output.
In future i think you can get more than one Stereo output, to create multiple Audio Effects with Clarity to playback files on separate outputs, or create Sourround Effects. On Theater or Musical Shows this is always helpful. This can substitute Audio Playback Software, too.